Posts Tagged ‘diabetes’

Cortisol- Its Role in Stress, Inflammation, and Indications for Diet Therapy

"Cortisol’s far-reaching, systemic effects play many roles in the body’s effort to carry out its processes and maintain homeostasis." Read the rest of this entry »

Gut Ecology Matters

"The portfolio of gut bacteria in patients with obesity and type 2 diabetes may look different from that of healthy people." Read the rest of this entry »

Coffee may reduce risk for type 2 diabetes

In the case of diabetes, the reasons behind the supposed protection conferred by coffee are not clear, but there are theories based on animal research. Read the rest of this entry »

Weight of the world: 2.1 billion people obese or overweight

"Obesity is a complex problem fueled by the availability of cheap, fatty, sugary, salty, high-calorie "junk food" and the rise of sedentary lifestyles. It is a major risk factor for heart disease and stroke, diabetes, arthritis and certain cancers." Read the rest of this entry »

Lifestyle change leads to improvement in Diabetes, Depression

When the status quo in one’s state of health is unacceptable, change is a welcome thing.  Identifying and making change happen can experienced as problematic.  Physical movement of any type is some form of physical change, if only in ending in a different state than when/where one started. Lifestyle change can be a tall order for most of us, however one may confidently begin with baby steps that cannot be denied, such as going for a walk, or making a conscious choice of whatever type.

Here is a study abstract that associates lifestyle change with improved outcomes for those with diabetes and depression diagnoses. Click on the URL below to gain access to the full text of this report.

Intensive Lifestyle Changes Lead to Lasting Improvement in T2DM
Reduction in incidence of mild or greater depression symptoms; improved physical function
MONDAY, June 2, 2014 (HealthDay News) — For obese/overweight adults with type 2 diabetes, an intensive lifestyle intervention (ILI) is associated with a reduced risk of incident depression and with better physical function, according to a study published in the June issue of Diabetes Care.

Thomas A. Wadden, Ph.D., from the University of Pennsylvania in Philadelphia, and colleagues compared the effects of an ILI with a diabetes support and education (DSE) control intervention on long-term changes in depression symptoms, antidepressant medication use, and health-related quality of life. Participants included 5,145 overweight/obese individuals with type 2 diabetes who were followed for a median of 9.6 years. They administered the Beck Depression Inventory (BDI) at baseline, annually at years one to four, and at year eight.

The researchers found that, compared with DSE, ILI correlated with a significant reduction in the incidence of mild or greater depression symptoms (BDI scores ≥10; hazard ratio, 0.85; P= 0.0145). Both groups experienced a worsening of Medical Outcome Study Short Form 36 (SF-36) physical component summary scores over time, but throughout the first eight years the ILI participants reported better physical function than DSE participants (all P values < 0.01). No significant between-group differences were seen in the proportion of participants who used antidepressant medications or in SF-36 mental component summary scores.

“These findings should be considered when evaluating the potential benefits of ILIs,” the authors write.

Several authors disclosed financial ties to the pharmaceutical and weight loss industries.

Sleep Apnea association with Diabetes Risk

Up to 30 percent higher chance of developing blood sugar disease seen in study, but findings aren't conclusive Read the rest of this entry »

Good Diets involve balanced intake of protein, carbohydrates and fats

People who eat the most protein, especially from animal sources, are more likely to be diagnosed with type 2 diabetes, according to a study of European adults Read the rest of this entry »

Mediterranean Diet and Diabetes Management

For people recently diagnosed with type 2 diabetes, eating lots of olive oil, fish and whole grains slows progression of the disease more than restricting fat Read the rest of this entry »

A dietary strategy to stabilize blood glucose levels for those with Type 2 Diabetes

New research presented at the June 2014 American Diabetes Association Scientific Sessions suggests that canola oil helps control blood glucose in people with Type 2 diabetes when it's incorporated into a low-glycemic index diet. Read the rest of this entry »

Good news for men who eat soy

Good news for men who eat soy.

As always soy in your diet is the best way to get it!

Soy Okay in Diabetic Men with Low Testosterone

Published: Jun 23, 2014

By Kristina Fiore, Staff Writer, MedPage Today

CHICAGO — Soy supplements won’t send testosterone levels plummeting in men with type 2 diabetes who already have low levels of the hormone, researchers reported here.

Testosterone levels actually rose with supplementation with either a soy protein bar or a soy protein bar that also contained phytoestrogens, Thozhukat Sathyapalan, MBBS, MD, of Hull York Medical School in England, and colleagues reported at the joint meeting of the Endocrine Society and the International Congress on Endocrinology here.

Some possible benefits in metabolic parameters were also seen with the phytoestrogen-containing soy bars, the group indicated.

“There’s no concern that soy will effect testosterone,” Sathyapalan said. “In fact, it can maybe have a positive effect.”

Some researchers have expressed concerns that the phytoestrogens in soy have estrogen-mimicking effects that may affect testosterone levels — particularly in men who already have low testosterone. These phytoestrogens include genistein and daidzein.

To assess whether these phytoestrogens can impact testosterone levels in men with type 2 diabetes who have borderline low testosterone levels, Sathyapalan and colleagues assessed 210 men with the condition who were between the ages of 55 and 70 and whose testosterone levels were below 12 nmol/L.

They were randomized to a 30-g soy protein cereal bar that either contained phytoestrogens (66 mg) or no phytoestrogens, eating two a day for the three months of the study.

Overall they saw an increase in testosterone levels in both study arms: “We thought there would be a reduction in testosterone levels, but there was an increase in testosterone levels in both groups,” Sathyapalan said at a press briefing.

Mean levels rose from 9.8 to 11.3 nmol/L in the combination group and from 9.2 to 10.3 nmol/L in the soy alone group, his group reported. No changes in estrogen levels were seen in either group.

The researchers also found that those taking the phytoestrogen bar had additional benefits in terms of metabolic parameters and cardiovascular risk.

Specifically, that group showed a significant drop in mean fasting plasma glucose, from 142 mg/dL to 116 mg/dL, compared with a slight uptick from 141 mg/dL to 151 mg/dL in the soy-alone group, as well as a drop in HbA1c not seen with soy alone.

Patients assigned to the phytoestrogen-containing bar also had a significant improvement in insulin sensitivity, with HOMA-IR scores falling from 7.2 to 2.5 compared with a rise from 10.2 to 11.3 for those on soy alone.

The phytoestrogens group also had a decrease in triglycerides, C-reactive protein, and diastolic blood pressure that wasn’t seen in the soy-alone group.

Sathyapalan said the results weren’t surprising given the fact that soy has long been used as a medical food in diabetes. He concluded, however, that further studies are needed to determine the differing effects of soy protein alone and soy protein plus phytoestrogens.

He added that he and his colleagues have also investigated the differences between these two cereal bars in postmenopausal women, finding that both improve bone turnover markers which could have implications for osteoporosis.

Another study, however, showed that soy supplementation may have ties to hypothyroidism; further study is needed to definitively determine if that is the case.

The study was supported by the Food Standards Agency in the U.K.

Sathyapalan reported no relevant financial disclosures.

Source reference: Sathyapalan T, et al “The effect of soy phytoestrogens on cardiovascular risk markers in men with type 2 diabetes and subclinical hypogonadism — A randomized double blind parallel study” ICE/ENDO 2014; Abstract SAT-0367